Lab archive
Research, people, funding, events, awards, and open resources from the Synthetic Physiology Lab, from June 2020 onward.
18 recent stories
Congratulations to Dr Eloisa Torchia and Dr Melissa Pezzotti, who defended their PhDs after four years of advancing SPL's engineered culture, mechanobiology, and live-imaging platforms. We are delighted that both are continuing the adventure with SPL.
Featured story plus 17 recent updates
Francesco gave an invited presentation at the 10th World Congress of Biomechanics in Vancouver, sharing SPL's cell-cycle-aware phenotyping platforms for tracking structural and functional changes in engineered tissues.
Francesco joined ERC Days at UNIVPM to discuss frontier-research funding, share experience of the ERC programme, and advocate for conditions that help ambitious research thrive in Italy.
Francesco discussed how artificial intelligence can expand experimental possibilities at the University of Pavia's event on AI in research, while keeping scientific judgment, empirical evidence, and the limits of the technology firmly in view.
Francesco presented SPL's work at Janelia's meeting on the intersection of mechanics and metabolism across biological scales, connecting engineered tissues with a broad community studying how physical context shapes cell state.
MicroSplit is published in Nature Methods, using semantic unmixing to recover richer biological information from multiplexed fluorescence images.
Micro-comb 3D printing is published in Biofabrication, introducing a rapid route to tissue-guiding substrates through micro-embossed printing nozzles.
Francesco, Eloisa, and Melissa presented SPL's work at TERMIS-EU 2026 in Palma de Mallorca, sharing new approaches to cell-cycle-aware imaging, intracellular mechanics, and engineered tissue models.
Our deep-learning workflow for multiplexed FUCCI imaging is published in npj Imaging, turning live-cell reporters into quantitative trajectories of cell state.
BIOPOINT is now published in PLOS Computational Biology, offering a particle-based framework for probing nuclear mechanics and cell–matrix interactions with experimentally grounded parameters.
VISTA is published in APL Bioengineering, integrating engineered confinement, live FUCCI imaging, and analysis to follow cell-cycle-aware phenotypes from experiment to quantitative readout.
Francesco gave an invited presentation at the Biophysical Society Bioengineering Subgroup meeting, sharing SPL's approach to rebuilding measurable physiology with engineered cells, materials, and imaging.
The CALIPERS FUCCIplex plasmids are now available through Addgene, making SPL's cell-cycle-aware live-imaging toolkit easier for other laboratories to adopt and extend.
Francesco has been elected Chair-Elect of the Biophysical Society Bioengineering Subgroup, supporting a community that connects physical principles, engineering, and living systems.
HYDRA is published in Communications Engineering, showing how robotic liquid handling can fabricate physiologically soft cell-culture hydrogels directly in high-throughput screening plates.
Alessandro Enrico and Sara Rigolli represented SPL at the UNLOOC and BEONCHIP meeting in Zaragoza, exchanging tools and standards for extracting more useful data from organ-on-chip systems.
Donato Giovannelli presented his work on microbial life in extreme environments, planetary-scale biogeochemical cycles, and the coevolution of the geosphere and biosphere in SPL's Through the Looking Glass seminar series.
The LigHTS preprint introduces massively parallel biomimetic photo-functionalization for imaging-based ultra-high-throughput screening.
No recent stories match this category.
Full archive
Every provisional story remains reachable on a stable year page without JavaScript. Search adds speed, not dependency.
Search the full archive