HYDRA preprint
The HYDRA preprint introduces robotic fabrication of thin, planar hydrogels in standard multiwell plates for physiologically relevant high-throughput drug testing.
The HYDRA preprint introduces robotic fabrication of thin, planar hydrogels in standard multiwell plates for physiologically relevant high-throughput drug testing.
The CALIPERS preprint introduces cell-cycle-aware live imaging for phenotyping and regeneration studies, linking multiplexed FUCCI reporters with reproducible analysis.
After three months of modeling pathogen–host interactions with SPL, Chimwemwe Msosa returns to Malawi. We thank him for a wonderful visit and wish him the very best in his next adventure.
SPL joins CARDINAL, a new European research programme developing advanced tools and models for more predictive, human-relevant biomedical research.
Congratulations to Sara Rigolli, who continues with SPL as a PhD student after completing her master's thesis on materials and microfabrication with the group.
Welcome to Tehreem Ali, who joins SPL through the One Health PhD programme, focusing on bioinformatics, single-cell transcriptomics, and spatial transcriptomics.
We thank Saranya Vasudevan for her contributions to computational modeling of biomaterials and engineered culture platforms during her time with SPL, and wish her every success in her next chapter.
Francesco presented SPL's work at the Human Cell Atlas meeting, contributing an extracellular-matrix perspective to the effort to map human cells in their native physical and molecular context.
Francesco gave an invited presentation at MBE24, sharing SPL's approach to combining engineered tissue systems, imaging, and computational biophysics.
Welcome to Chimwemwe Msosa from the Malawi University of Business and Applied Sciences, who joins SPL for a CICOPS research visit focused on analytical models of pathogen–host interactions.
Francesco presented SPL's work at NanoInnovation 2024, connecting engineered biomaterials and high-throughput tissue models with Italy's nanotechnology community.
Our active-stress isogeometric shell model is published in Mechanics of Materials, enabling efficient simulations of muscular thin films and cardiac electromechanics.
Francesco presented on the human and creative skills behind interdisciplinary research, reflecting on how teams turn scientific imagination into reproducible engineering.
Moises presented SPL's work at ISSCR 2024 in Hamburg, introducing an engineered human stem-cell line for tracking structure, function, and cell-cycle progression during development and morphogenesis.
Francesco presented SPL's work at the European Society of Biomechanics Congress in Edinburgh, connecting subcellular-element models with multiscale cell and tissue mechanics in morphogenesis.
We thank Bohdana Horda for her work on hydrogel fabrication and engineered cell-culture platforms during her time with SPL, and wish her every success in her next chapter.
Francesco gave an invited presentation at CIMTEC, sharing SPL's work on engineered matrices and scalable human tissue models.
Moises presented SPL's work at SIBBM Frontiers in Molecular Biology in Trento, bringing the TEMPO engineered stem-cell platform to a community studying development, homeostasis, and ageing.
Claudia Marenco presented ‘ERC Frontier Research’ in SPL's Through the Looking Glass seminar series, opening a discussion about frontier funding and the conditions that help ambitious research thrive.
UNLOOC is underway. SPL joins a European consortium working to unlock the data content of organ-on-chip systems and make complex models more useful for biomedical discovery.
SPL has received an ERC Proof of Concept grant for hiPSCmore, advancing instrumented human stem cells for richer readouts in high-throughput drug discovery and regenerative medicine.
Francesco and Melissa presented SPL's work at Focus on Microscopy 2024 in Genoa, sharing new imaging tools for morphogenesis and smarter live imaging of cell division.
Francesco and Eloisa presented SPL's work at Nanoengineering for Mechanobiology in Camogli, connecting new approaches to morphogenesis with automated hydrogel culture for high-throughput screening.
Emanuele Carnevale Baraglia continues with SPL as a PhD student, developing computational models that connect organelle physiology with experimentally testable mechanisms.
When art and science collide is published in Biophysical Reviews, reflecting on how visualization, creativity, and experimental discipline belong to one scientific practice.
Loris Rizzello presented his work on host–pathogen interactions and nanotechnology-based approaches to infectious and pandemic diseases in SPL's Through the Looking Glass seminar series.